BTK-IN-27

CAT: 0804-HY-156553Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-156553Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM) . BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50: [1].

CAS Number

1841502-36-0

UNSPSC

12352005

Target

Btk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/btk-in-27.html

Solubility

10 mM in DMSO

Smiles

NC1=C2C(N([C@H]3CN(CCC3)C(C=C)=O)N=C2C4=CC=C(C=C4)CNC(C5=CC=C(C=C5)C(C)(C)C)=O)=NC=N1

Molecular Formula

C31H35N7O2

Molecular Weight

537.66

References & Citations

[1]Mathew CALDER, et al. Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase. Patent. WO2015189620.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products