BTK-IN-27

• UNSPSC Description:

  BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM). BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50: [1].

• Target Antigen:

  Btk

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/btk-in-27.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=C2C(N([C@H]3CN(CCC3)C(C=C)=O)N=C2C4=CC=C(C=C4)CNC(C5=CC=C(C=C5)C(C)(C)C)=O)=NC=N1

• Molecular Weight:

  537.66

• References & Citations:

  [1]Mathew CALDER, et al. Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase. Patent. WO2015189620.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1841502-36-0