BTK-IN-16

CAT: 0804-HY-151211-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-151211-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-16 is a dual inhibitor of BTK wild type and C481S mutant of Bruton’s tyrosine kinase (BTK) with IC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia[1].
CAS Number
[2883232-92-4]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-in-16.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C(C=C1OC)=NC=N2)=C2NC3=CC=CN=C3
Molecular Formula
C15H14N4O2
Molecular Weight
282.30
References & Citations
[1]Kim T, et al. Two-Track Virtual Screening Approach to Identify the Dual Inhibitors of Wild Type and C481S Mutant of Bruton's Tyrosine Kinase. J Chem Inf Model. 2022 Aug 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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