Beclin1-Bcl-2 interaction inhibitor 1

Beclin1-Bcl-2 interaction inhibitor 1

• UNSPSC Description: Beclin1-Bcl-2 interaction inhibitor 1 potently inhibits Beclin 1/Bcl-2 binding. Beclin1-Bcl-2 interaction inhibitor 1 can be used for the research of cancer and neurodegeneration[1].
• Target Antigen: Bcl-2 Family; Beclin1
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/beclin1-bcl-2-interaction-inhibitor-1.html
• Solubility: 10 mM in DMSO
• Smiles: [H][C@]1(CC(C2=CC=C(NC(OC(C)C)=O)C=C2)=NN1C(C3=CC=C(Br)C=C3)=O)C4=CC=CC=C4
• Molecular Weight: 506.39
• References & Citations: [1]Pan YZ, et al. Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol. 2023 Oct 24;6(1):1080.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported