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Prasugrel-d4

CAT: 0804-HY-15284S2-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15284S2-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prasugrel-d4 is the deuterium labeled Prasugrel[1]. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[2].
CAS Number
1189919-49-0
Product Name Alternative
PCR 4099-d4
UNSPSC
12352005
Target
P2Y Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O=C(C1C([2H])([2H])C1([2H])[2H])C(C2=C(C=CC=C2)F)N3CC4=C(SC(OC(C)=O)=C4)CC3
Molecular Formula
C20H16D4FNO3S
Molecular Weight
377.47
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wijeyeratne YD, et al. Anti-platelet therapy: ADP receptor antagonists. Br J Clin Pharmacol. 2011 Oct;72 (4) :647-57.|[3]Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5 (7) :1545-51.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported