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Prasugrel-d3

CAT: 0804-HY-15284S1-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15284S1-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prasugrel-d3 is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].
CAS Number
1127253-02-4
Product Name Alternative
PCR 4099-d3
UNSPSC
12352005
Target
P2Y Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Purity
98.58
Solubility
10 mM in DMSO|DMF : ≥ 5mg/mL
Smiles
O=C(OC(S1)=CC2=C1CCN(C(C3=CC=CC=C3F)C(C4CC4)=O)C2)C([2H])([2H])[2H]
Molecular Formula
C20H17D3FNO3S
Molecular Weight
376.46
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Wijeyeratne YD, et al. Anti-platelet therapy: ADP receptor antagonists. Br J Clin Pharmacol. 2011 Oct;72 (4) :647-57.|[3]Sugidachi A, et al. The greater in vivo antiplatelet effects of prasugrel as compared to clopidogrel reflect more efficient generation of its active metabolite with similar antiplatelet activity to that of clopidogrel's active metabolite. J Thromb Haemost. 2007 Jul;5 (7) :1545-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
P2Y12 Receptor

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