2’-β-C-Ethynyladenosine

CAT: 0804-HY-152475-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-152475-01Size:5 mg
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Description
2’-β-C-Ethynyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-β-C-Ethynyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[640725-76-4]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-β-c-ethynyladenosine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](CO)O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@]1(C#C)O
Molecular Formula
C12H13N5O4
Molecular Weight
291.26
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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