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2’-β-C-Ethynylcytidine

CAT: 0804-HY-152474Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152474Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2’-β-C-Ethynylcytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-β-C-Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
188413-99-2
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-β-c-ethynylcytidine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](CO)O[C@@H](N2C(N=C(N)C=C2)=O)[C@]1(C#C)O
Molecular Formula
C11H13N3O5
Molecular Weight
267.24
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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