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ASPER-29

CAT: 0804-HY-152210Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152210Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].
CAS Number
2630388-03-1
UNSPSC
12352005
Target
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/asper-29.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1)N[C@@H](C(OC[C@H](NS(=O)(C2=CC=C(C=C2)Br)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4
Molecular Formula
C31H29BrN2O5S
Molecular Weight
621.54
References & Citations
[1]Haoqiang Huang, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cathepsin L; Cathepsin S

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