ASPER-29

• Description:

  ASPER-29 is Asperphenamate HY-129578 analog. ASPER-29 also is a dual cathepsin L and S inhibitor with IC50 value of 6.03 μM and 5.02 μM, respectively. ASPER-29 can be used for the research of the migration and invasion of cancer[1].

• UNSPSC:

  12352005

• Target:

  Cathepsin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/asper-29.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CC=C1)N[C@@H](C(OC[C@H](NS(=O)(C2=CC=C(C=C2)Br)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4

• Molecular Formula:

  C31H29BrN2O5S

• Molecular Weight:

  621.54

• References & Citations:

  [1]Haoqiang Huang, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Cathepsin L; Cathepsin S

• CAS Number:

  [2630388-03-1]