PI3K/VEGFR2-IN-1

• UNSPSC Description:

  PI3K/VEGFR2-IN-1 is a potent dual PI3K/VEGFR2 inhibitor with IC50 values of 2.21 and 68 μM for PI3K and VEGFR2, respectively. PI3K/VEGFR2-IN-1 induces apoptosis. PI3K/VEGFR2-IN-1 can be used in research of cancer[1].

• Target Antigen:

  Apoptosis; PI3K; VEGFR

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3k-vegfr2-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  S=C(N/N=C(C1=CC2=CC=CC=C2O1)\C)NC3=CC=C(Cl)C=C3

• Molecular Weight:

  343.83

• References & Citations:

  [1]El-Khouly OA, et, al. Design, synthesis and computational study of new benzofuran hybrids as dual PI3K/VEGFR2 inhibitors targeting cancer. Sci Rep. 2022 Oct 12;12(1):17104.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2851067-08-6