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VEGFR2-IN-1

CAT: 0804-HY-145849-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145849-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VEGFR2-IN-1 is a potent and selective VEGFR2 inhibitor (IC50=19.8 nM) . VEGFR2-IN-1 inhibits cell proliferation and migration through apoptosis activation and VEGFR2 inhibition[1].
CAS Number
2765224-55-1
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr2-in-1.html
Solubility
10 mM in DMSO
Smiles
C=CCSC1=NN=C(N1/N=C/C2=CNC3=CC=CC=C23)C4=CC5=CC=CC=C5N4
Molecular Formula
C22H18N6S
Molecular Weight
398.48
References & Citations
[1]Nafie MS, Boraei ATA. Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer. Bioorg Chem. 2022; 122:105708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1

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