VEGFR2-IN-1

• UNSPSC Description:

  VEGFR2-IN-1 is a potent and selective VEGFR2 inhibitor (IC50=19.8 nM). VEGFR2-IN-1 inhibits cell proliferation and migration through apoptosis activation and VEGFR2 inhibition[1].

• Target Antigen:

  VEGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vegfr2-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C=CCSC1=NN=C(N1/N=C/C2=CNC3=CC=CC=C23)C4=CC5=CC=CC=C5N4

• Molecular Weight:

  398.48

• References & Citations:

  [1]Nafie MS, Boraei ATA. Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer. Bioorg Chem. 2022; 122:105708.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2765224-55-1