PI3Kα-IN-1

PI3Kα-IN-1

• CAS Number: 2100855-80-7
• UNSPSC Description: PI3Kα-IN-1 is a PI3Kα inhibitor (IC50 IC50: 104 nM)[1].
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3kα-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC(NC1=CC=C(NC(NC2=CC=C(C3=NC(N4CCOCC4)=C5C(C=CC=N5)=N3)C=C2)=O)C=C1)=O
• Molecular Weight: 483.52
• References & Citations: [1]Al-Ashmawy AAK, et al. Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3117-3122.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported