CDK1-IN-4
CAT:
804-HY-151408
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK1-IN-4
- CAS Number: 3032997-16-0
- UNSPSC Description: CDK1-IN-4 (10d) is a selective CDK1 inhibitor with IC50s of 44.52, 624.93 and 135.22 nM for CDK1, CDK2 and CDK5, respectively. CDK1-IN4 inhibits the growth of cancer cells by affecting cell cycle. CDK1-IN-4 can be used for the research of cancer[1].
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk1-in-4.html
- Solubility: 10 mM in DMSO
- Smiles: S=C(N1CCN(C2=NN=C(CC3=CC=CC=C3)C4=C2C=CC=C4)CC1)NC5=CC=CC(Cl)=C5
- Molecular Weight: 474.02
- References & Citations: [1]Akl L, et al. Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer. Eur J Med Chem. 2022 Aug 31;243:114704.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported