CDK1/2/4-IN-1

CAT: 0931-T60583-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T60583-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2414633-49-9

Target

Others, Apoptosis, Caspase, Bcl-2 Family, CDK

Related Pathways

Others, Proteases/Proteasome, Apoptosis, Cell Cycle/Checkpoint

Bioactivity

CDK1/2/4-IN-1 (compound 3a) is a potent CDK inhibitor with IC50 values of 1.47, 0.78, and 0.87 μM for CDK1, CDK2, and CDK4, respectively. It can be used in cancer research to arrest the cell cycle at the G2/M phase and induce apoptosis, elevating Bax, caspase-3, and P53 levels while decreasing Bcl-2 levels [1].

Smiles

C(/C=C/C1=CC=C(OC)C=C1)(=O)C=2N=C(NC)SC2C

Molecular Formula

C15H16N2O2S

Molecular Weight

288.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-146253	CDK1/2/4-IN-1
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