CDK1-IN-8

• Description:

  CDK1-IN-8 is a CDK1 inhibitor. CDK1-IN-8 inhibits cell migration, induces apoptosis, and arrests the cell cycle at the G2/M phase. CDK1-IN-8 leads to a significant downregulation of CDK1 protein levels in HepG2 cells. CDK1-IN-8 can be used for the study of human hepatocellular carcinoma[1].

• UNSPSC:

  12352128

• Target:

  Apoptosis; CDK

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Smiles:

  OC1=C2C(C(C(C=C(C(NCCNC(C3=CC(F)=C(Cl)C=C3)P(OCC)(OCC)=O)=O)C=C4O)=C4C2=O)=O)=CC=C1

• Molecular Formula:

  C28H27ClFN2O8P

• Molecular Weight:

  604.95

• References & Citations:

  [1]Li J, et al. Design, synthesis, and evaluation of phosphorylated rhein derivatives with enhanced antiproliferative activity. Bioorg Chem. 2025 Nov;166:109172.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK1

• CAS Number:

  [3077717-99-5]