BCP-T.A

CAT: 0804-HY-151212Size: 1 mgDry Ice: NoHazardous: No

CAT#: HY-151212Size: 1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

BCP-T.A, a tunable heterocyclic electrophile, is a potent ferroptosis inducer by binding to GPX4[1]. BCP-T.A is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CAS Number

[2786829-70-5]

UNSPSC

12352005

Target

Ferroptosis; Glutathione Peroxidase

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcp-t-a.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)CC1)C4=CSC(C#C)=N4

Molecular Formula

C23H19Cl2N3OS

Molecular Weight

456.39

References & Citations

[1]Endri Karaj, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. J Med Chem. 2022 Aug 19.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GPX4

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