Cys-C-cGMP

Cys-C-cGMP

• CAS Number: 2241669-85-0
• UNSPSC Description: Cys-C-cGMP is a autophagy tag for AUTACs. Cys-C-cGMP can increase the K63-linked ubiquitination of mitochondria in HeLa cells[1].
• Target Antigen: AUTACs
• Type: Reference compound
• Related Pathways: Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cys-c-cgmp.html
• Solubility: 10 mM in DMSO
• Smiles: NC(N1)=NC2=C(N=C(SC[C@H](NC(C)=O)C(O)=O)N2[C@H]3[C@H](O)[C@H](OP4(O)=O)[C@@H](CO4)O3)C1=O
• Molecular Weight: 506.38
• References & Citations: [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported