Cys-C-cGMP

• Description :

  Cys-C-cGMP is a autophagy tag for AUTACs. Cys-C-cGMP can increase the K63-linked ubiquitination of mitochondria in HeLa cells[1].

• UNSPSC :

  12352005

• Target :

  AUTACs

• Type :

  Reference compound

• Related Pathways :

  Autophagy; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cys-c-cgmp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NC(N1)=NC2=C(N=C(SC[C@H](NC(C)=O)C(O)=O)N2[C@H]3[C@H](O)[C@H](OP4(O)=O)[C@@H](CO4)O3)C1=O

• Molecular Formula :

  C15H19N6O10PS

• Molecular Weight :

  506.38

• References & Citations :

  [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76 (5) :797-810.e10.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2241669-85-0]