Cys-C-cGMP

• UNSPSC Description:

  Cys-C-cGMP is a autophagy tag for AUTACs. Cys-C-cGMP can increase the K63-linked ubiquitination of mitochondria in HeLa cells[1].

• Target Antigen:

  AUTACs

• Type:

  Reference compound

• Related Pathways:

  Autophagy;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cys-c-cgmp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(N1)=NC2=C(N=C(SC[C@H](NC(C)=O)C(O)=O)N2[C@H]3[C@H](O)[C@H](OP4(O)=O)[C@@H](CO4)O3)C1=O

• Molecular Weight:

  506.38

• References & Citations:

  [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2241669-85-0