Probe-Cys

• UNSPSC Description:

  Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/probe-cys.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=CO1)OC2=CC(OC3=C4/C=C/C(C(C)(C5=CC=CC=C56)C)=[N+]6CCCCS(=O)([O-])=O)=C(C=C3CC4)C=C2

• Molecular Weight:

  585.67

• References & Citations:

  [1]Jia D, et al. Near-Infrared Fluorescence Probe with a New Recognition Moiety for the Specific Detection of Cysteine to Study the Corresponding Physiological Processes in Cells, Zebrafish, and Arabidopsis thaliana. Anal Chem. 2024;96(15):6030-6036.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported