PET-cGMP

• Description:

  PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM[1].

• UNSPSC:

  12352005

• Target:

  PKG

• Related Pathways:

  Stem Cell/Wnt

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2

• Molecular Formula:

  C18H16N5O7P

• Molecular Weight:

  445.32

• References & Citations:

  [1]James C Campbell, et al. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017 Sep 15;12 (9) :2388-2398.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  78080-27-0