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PET-cGMP

CAT: 0804-HY-137665Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137665Size:1 Each
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Description
PET-cGMP is a cyclic guanosine monophosphate analog and an effective selective agonist of PKG I, the EC50 of PET-cGMP for PKG Iβ is 3.8 nM, while for PKG II, it's 193 nM[1].
CAS Number
78080-27-0
UNSPSC
12352005
Target
PKG
Related Pathways
Stem Cell/Wnt
Field of Research
Cardiovascular Disease
Smiles
O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2
Molecular Formula
C18H16N5O7P
Molecular Weight
445.32
References & Citations
[1]James C Campbell, et al. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017 Sep 15;12 (9) :2388-2398.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
BLG-P001-50PET-cGMP
BLG-P003-108-Br-PET-cGMP
BLG-P054-05PET-cGMP-8-TMAmd- (EO) 8-EAmdMT-8-cGMP-PET
BLG-C045-258-pCPT-PET-cGMP
BLG-P059-01PET-cGMP-8-TMAmd- (PEG pd 2000) -AmdMT-8-cGMP-PET
BLG-F012-018-[Fluo]-AHT-PET-cGMP
BLG-A102-054-N3-PET-8-Br-cGMP
439977-018-Br-PET-cGMP Sodium Salt
BLG-A186-0014-N3-PET-8-Biotin-11-cGMP
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