M1/M4 muscarinic agonist 1

• UNSPSC Description:

  M1/M4 muscarinic agonist 1 (compound 41) is a selective muscarinic M4/M1 agonist with EC50 values of 14 and 55 nM for M4 and M1, respectively. M1/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusional disorder, etc[1].

• Target Antigen:

  mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/m1-m4-muscarinic-agonist-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC(N1CC2(C[C@H](N3CCC(C4=CC=CC=C4OCC)CC3)CC2)C1)=O

• Molecular Weight:

  370.53

• References & Citations:

  [1]Christopher G Thomson, et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. ACS Med. Chem. Lett. 2023. Nov 6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported