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Edoxaban M4

CAT: 0804-HY-119124-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119124-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor [1][2].
CAS Number
834919-19-6
Product Name Alternative
D21-2393
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/edoxaban-m4.html
Purity
99.13
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)[C@@H]1C[C@H]([C@H](CC1)NC(C(NC2=NC=C(C=C2)Cl)=O)=O)NC(C3=NC4=C(CN(CC4)C)S3)=O
Molecular Formula
C22H25ClN6O5S
Molecular Weight
520.99
Precautions
H302, H315, H319, H335
References & Citations
[1]Romain Siriez, et al. Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method. J Thromb Thrombolysis. 2020 Apr;49 (3) :395-403.|[2]Kathrin I Foerster, et al. Simultaneous quantification of direct oral anticoagulants currently used in anticoagulation therapy. J Pharm Biomed Anal. 2018 Jan 30;148:238-244.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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