Products for Research Use Only
RegisterLogin

TLR4 agonist-1

CAT: 0804-HY-149650Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-149650Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TLR4 agonist-1 (compound 17a) is a potent agonist of Toll-like Receptor 4 (TLR4), and induces the generation of MIP-1β in RAW 264.7 and MM6 cells[1].
CAS Number
2374139-51-0
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr4-agonist-1.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]1O[C@@H](OC[C@@H](C(O)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@@H]1OP(O)(O)=O
Molecular Formula
C81H158N3O15P
Molecular Weight
1445.11
References & Citations
[1]Khalaf JK, et al. Diamino Allose Phosphates: Novel, Potent, and Highly Stable Toll-like Receptor 4 Agonists. J Med Chem. 2023;66 (20) :13900-13917.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-111358-01TLR7 agonist 1
HY-163829TLR2 agonist 1
HY-103698-01TLR7/8 agonist 1
HY-163998TLR4-IN-1
HY-103698A-01TLR7/8 agonist 1 (dihydrochloride)
HY-128598-01MD2-TLR4-IN-1
HY-153070TLR7 agonist 5
HY-153072TLR7 agonist 7
HY-173070TLR7 agonist 29
HY-152726TLR7 agonist 9

Alternative Products

CatalogName
T80978-01TLR4 agonist-1
T80977-01TLR4 agonist-1 TEA
T212514-01NOD2/TLR4 agonist-1
GTR19239336-01TLR4-IN-1
BA6304-50MD2-TLR4-IN-1
sc-52962TLR4 (76B357.1)

Popular Products