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TLR2 agonist 1

CAT: 0804-HY-163829Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163829Size:1 Each
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Description
TLR2 agonist 1 (Compound R-7d) is an agonist for human toll-like receptor 2 (TLR 2) with an EC50 of 116 pM. TLR2 agonist 1 enhances NF-κB promoter activation through TLR2/TLR1 heterodimers[1].
UNSPSC
12352211
Target
NF-κB; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr2-agonist-1.html
Smiles
O[C@@H]([C@@H](O1)OC[C@H](O)COC(CCCCCCCCCCC)=O)[C@@H](O)[C@@H]1[C@@H]2O[C@H](CCCCCCCCCCCC)OC2
Molecular Formula
C34H64O9
Molecular Weight
616.87
References & Citations
[1]Jia H, et al., The Development of a Highly Potent and Selective Human Toll-like Receptor 2 Agonist: Synthesis and Biological Evaluation of CaLGL-1 and Its Derivatives. J Med Chem. 2024 Jul 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR2

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