PI3Kδ-IN-17

PI3Kδ-IN-17

• CAS Number: 2768181-63-9
• UNSPSC Description: PI3Kδ-IN-17 (Compound S5) is a potent inhibitor of PI3Kδ, with IC50 of 2.82 nM. PI3Kδ-IN-17 shows strong inhibitory activity of proliferation in SU-DHL-6 cells (IC50=0.035 μM)[1].
• Target Antigen: PI3K
• Type: Reference compound
• Related Pathways: PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/pi3kδ-in-17.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1C[C@@H](NC2=C3C(C=CC(C4=CC(C(F)(F)F)=C(OC)N=C4)=N3)=NC=N2)CC1)[C@H]5NCCC5
• Molecular Weight: 487.48
• References & Citations: [1]Huanrong Bai, et al. Discovery of novel pyrido[3,2-d]pyrimidine derivatives as selective and potent PI3Kδ inhibitors. Drug Dev Res. 2023 Sep 21.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported