ROS 234

• Target :

  Others|||Histamine Receptor

• Related Pathways :

  Others|||Immunology/Inflammation|||Neuroscience|||GPCR/G Protein

• Bioactivity :

  ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].

• Smiles :

  N(CCCC1=CN=CN1)C=2NC=3C(N2)=CC=CC3

• Molecular Formula :

  C13H15N5

• Molecular Weight :

  241.29

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  184576-87-2