ROS 234

CAT: 0931-MF-0137724-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0137724-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
184576-87-2
Target
Others|||Histamine Receptor
Related Pathways
Others|||Immunology/Inflammation|||Neuroscience|||GPCR/G Protein
Bioactivity
ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].
Smiles
N(CCCC1=CN=CN1)C=2NC=3C(N2)=CC=CC3
Molecular Formula
C13H15N5
Molecular Weight
241.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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