AChE/BChE-IN-11

AChE/BChE-IN-11

• CAS Number: 80443-12-5
• UNSPSC Description: AChE/BChE-IN-11 (compound 1) is a potent is a dual AChE and BChE inhibitor with IC50 values of 70 and 71 μM for AChE and BChE, respectively. AChE/BChE-IN-11 is a natural product that could be isolated from the leaf of artichoke . AChE/BChE-IN-11 can be used in research of Alzheimer’s disease (AD) research[1].
• Target Antigen: Cholinesterase (ChE)
• Type: Natural Products
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/ache-bche-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=CC(O)=C2C(O[C@H](C3=CC(O)=C(O)C(O)=C3)[C@@H](O[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4)C2=O)=C1
• Molecular Weight: 466.39
• References & Citations: [1]Elsebai MF, et, al. X-ray crystalographic data, absolute configuration, and anticholinesterase effect of dihydromyricitrin 3-O-rhamnoside. Sci Rep. 2022 Nov 1;12(1):18351.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported