LE 28

• Description :

  LE 28 is a selective and activity-dependent legumain probe. LE 28 becomes fluorescent only upon binding active legumain. LE 28 can be used for research of cancers and inflammatory diseases[1].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye; Legumain

• Type :

  Dye Reagents

• Related Pathways :

  Neuronal Signaling; Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/le-28.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S(C1=C(C=CC=C1)C2=C(C=CC(N3C4=CC=CC=C4CC3)=C5)C5=[O+]C6=C2C=CC(N7C8=CC=CC=C8CC7)=C6)(N9CCC(CC9)C(NCCCNC(C%10=CC(C)=C(C(C)=C%10)C(OCC([C@H](CC(O)=O)NC([C@H]%11N(CCC%11)C([C@H](CCC(O)=O)NC(CCCCC[N+]%12=C(/C=C/C=C/C=C%13N(C%14=CC=C(S(=O)(O)=O)C=C%14C\%13(C)C)CC)C(C)(C)C%15=CC(S(=O)([O-])=O)=CC=C%12%15)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C102H111N10O21S3+

• Molecular Weight :

  1909.22

• References & Citations :

  [1]Edgington LE, et al. Functional imaging of legumain in cancer using a new quenched activity-based probe. J Am Chem Soc. 2013 Jan 9;135 (1) :174-82.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [1416080-97-1]