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FGFR3-IN-4

CAT: 0804-HY-148778Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-148778Size:1 Each
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Description
FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
CAS Number
2833706-13-9
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr3-in-4.html
Solubility
10 mM in DMSO
Smiles
C[C@H](C1=C(C=CC=C1)C#N)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(Cl)C=N5
Molecular Formula
C26H24ClN7O
Molecular Weight
485.97
References & Citations
[1]Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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