DMX-129

• Description :

  DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of [1].

• UNSPSC :

  12352005

• Target :

  IKK

• Type :

  Reference compound

• Related Pathways :

  NF-κB

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/dmx-129.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N#CC1=C(N2CC[C@@H](C2)F)N=CC(C3=NC(NC4=CN=C(N)C=C4)=NC=C3)=C1

• Molecular Formula :

  C19H17FN8

• Molecular Weight :

  376.39

• References & Citations :

  [1]Gary Karl Newton, et al. Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms. Patent WO2014128486A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1623123-95-4]