DMX-129

• Description:

  DMX-129 is an ΙΚΚε and TBK-1 inhibitor with IC50 values of [1].

• UNSPSC:

  12352005

• Target:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dmx-129.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C (N2CC[C@@H] (C2) F) N=CC (C3=NC (NC4=CN=C (N) C=C4) =NC=C3) =C1

• Molecular Formula:

  C19H17FN8

• Molecular Weight:

  376.39

• References & Citations:

  [1]Gary Karl Newton, et al. Pyrimidine compounds useful in the treatment of diseases mediated by ikke and/or tbk1 mechanisms. Patent WO2014128486A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1623123-95-4