TG6-129

• UNSPSC Description:

  TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages[1].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tg6-129.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC(NC1=CC=C(S(=O)(NC2=NN=C(CC)S2)=O)C=C1)=S)/C=C/C3=CC=C(F)C=C3

• Molecular Weight:

  491.58

• References & Citations:

  [1]Ganesh T, et al. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. ACS Med Chem Lett. 2013 Jul 11;4(7):616-621.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1164464-14-5