TG6-129

• Description :

  TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages[1].

• UNSPSC :

  12352005

• Target :

  Prostaglandin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/tg6-129.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC(NC1=CC=C(S(=O)(NC2=NN=C(CC)S2)=O)C=C1)=S)/C=C/C3=CC=C(F)C=C3

• Molecular Formula :

  C20H18FN5O3S3

• Molecular Weight :

  491.58

• References & Citations :

  [1]Ganesh T, et al. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. ACS Med Chem Lett. 2013 Jul 11;4 (7) :616-621.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EP

• CAS Number :

  [1164464-14-5]