TG6-129

CAT: 0804-HY-18970Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-18970Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TG6-129 is a selective antagonist of the EP2 receptor. TG6-129 reduces the expression of inflammatory factors induced by butaprost in P388D1 macrophages[1].
CAS Number
[1164464-14-5]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tg6-129.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(NC1=CC=C(S(=O)(NC2=NN=C(CC)S2)=O)C=C1)=S)/C=C/C3=CC=C(F)C=C3
Molecular Formula
C20H18FN5O3S3
Molecular Weight
491.58
References & Citations
[1]Ganesh T, et al. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. ACS Med Chem Lett. 2013 Jul 11;4 (7) :616-621.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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