Antibacterial agent 129

• Description :

  Antibacterial agent 129, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis and B. subtilis with MICs of 31.25 μM and 31.5 μM and . Antibacterial agent 129 shows good antifungal activity against A. niger with a MIC of 31.25 μM. Antibacterial agent 129 shows excellent antimycobacterial activity with MIC 57.73 μM for M. tuberculosis H37Rv[1].

• UNSPSC :

  12352005

• Target :

  Antibiotic; Bacterial; Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/antibacterial-agent-129.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC=CC=C5)F

• Molecular Formula :

  C26H21F2NO3

• Molecular Weight :

  433.45

• References & Citations :

  [1]Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3- (2- (3- (Substituted benzyloxy) oxetan-3-yl) -3-fluorophenoxy) -8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7 (50) :47096-47107.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2874263-66-6]