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EGFR-IN-67

CAT: 0804-HY-147996Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147996Size:1 Each
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Description
EGFR-IN-67 (Compound 7d) is a potent EGFR inhibitor with an IC50 of 0.34 μM. EGFR-IN-67 shows anticancer activity[1].
CAS Number
2416924-99-5
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-67.html
Solubility
10 mM in DMSO
Smiles
S=C(N1N=C(C2=CC=CC=C2)CC1/C=C/C3=CC=CC=C3)N
Molecular Formula
C18H17N3S
Molecular Weight
307.41
References & Citations
[1]George RF, et al. Some 1,3,5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Bioorg Chem. 2020 Jun;99:103780.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1

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Alternative Products

CatalogName
T60729-01EGFR-IN-67
WT0116Tongue Cancer: P40, CK5/6, P16, EGFR, Ki-67
030367Ki-67 (Antigen KI-67, MKI67, Ki67, Ki 67)
223782-01Ki-67 (Antigen KI-67, MKI67, Ki67, Ki 67) discontinued
MBS2122915-01Recombinant Ki-67 Protein (Ki-67)
MBS2124331-01Eukaryotic Ki-67 Protein (Ki-67)
TRV-032601-01Active Ki-67 Protein (Ki-67)
169870-01Ki-67 (Antigen KI-67) discontinued
BA6383-25YS-67
C3246-25ACS 67

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