HCA VB-IN-1

• Description :

  HCA VB-IN-1 (compound 15) is a potent and selective hCA VB (carbonic anhydrase) inhibitor, with a KI of 515.7 nM[1].

• UNSPSC :

  12352005

• Target :

  Carbonic Anhydrase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/hca-vb-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC=C(C(C)=C1)NC(NOS(N)(=O)=O)=O

• Molecular Formula :

  C9H13N3O4S

• Molecular Weight :

  259.28

• References & Citations :

  [1]Poli G, et al. N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. Bioorg Chem. 2020 Jul;100:103896.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported