hCA VB-IN-1

hCA VB-IN-1

• UNSPSC Description: hCA VB-IN-1 (compound 15) is a potent and selective hCA VB (carbonic anhydrase) inhibitor, with a KI of 515.7 nM[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/hca-vb-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=CC=C(C(C)=C1)NC(NOS(N)(=O)=O)=O
• Molecular Weight: 259.28
• References & Citations: [1]Poli G, et al. N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. Bioorg Chem. 2020 Jul;100:103896.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported