HCA VB-IN-1

• Description:

  HCA VB-IN-1 (compound 15) is a potent and selective hCA VB (carbonic anhydrase) inhibitor, with a KI of 515.7 nM[1].

• UNSPSC:

  12352005

• Target:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hca-vb-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC=C(C(C)=C1)NC(NOS(N)(=O)=O)=O

• Molecular Formula:

  C9H13N3O4S

• Molecular Weight:

  259.28

• References & Citations:

  [1]Poli G, et al. N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. Bioorg Chem. 2020 Jul;100:103896.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported