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HCA VB-IN-1

CAT: 0804-HY-147956Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147956Size:1 Each
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Description
HCA VB-IN-1 (compound 15) is a potent and selective hCA VB (carbonic anhydrase) inhibitor, with a KI of 515.7 nM[1].
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hca-vb-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C(C)=C1)NC(NOS(N)(=O)=O)=O
Molecular Formula
C9H13N3O4S
Molecular Weight
259.28
References & Citations
[1]Poli G, et al. N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions. Bioorg Chem. 2020 Jul;100:103896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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