HCA-6

• Description :

  HCA-6 is a calcium-channel and P-glycoprotein blocker. HCA-6 can induce cancer cells apoptosis and increase anticancer activity of Cisplatin (HY-17394) . HCA-6 also exhibits antibacterial activity against Bacillus subtilis. HCA-6 can be used for the research of cancer and infection, such as breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Bacterial; Calcium Channel; P-glycoprotein

• Related Pathways :

  Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Cancer; Infection

• Smiles :

  O[C@@H]1[C@H](O)[C@@H](COC(COC2=CC=C(C3C(C(OCC)=O)=C(C)NC(C)=C3C(OCC)=O)C=C2[N+]([O-])=O)=O)O[C@H]1N(C(N4)=O)C=C(F)C4=O

• Molecular Formula :

  C30H33FN4O14

• Molecular Weight :

  692.60

• References & Citations :

  [1]Chen G, et al. Novel dihydropyridines as potential calcium-channel and P-glycoprotein blockers applicable for chemotherapy sensitization. Bioorg Chem. 2025 Oct;165:109072.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported