PI3Kα-IN-6
CAT:
804-HY-147767
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PI3Kα-IN-6
- CAS Number: 2272894-14-9
- UNSPSC Description: PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor. PI3Kα-IN-6 exhibits anticancer potential and no toxicity in normal cells. PI3Kα-IN-6 increases generation of ROS, reduces mitochondrial membrane potential (MMP) and induces apoptosis[1].
- Target Antigen: Apoptosis; PI3K; Reactive Oxygen Species
- Type: Reference compound
- Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3kα-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC=C(C=C1)SCC2=C(N=C3C=CC(C)=CN32)I
- Molecular Weight: 410.27
- References & Citations: [1]Singh D, et al. Synthesis of 3-N-/O-/S-methyl-imidazo[1,2-a] pyridine derivatives for caspase-3 mediated apoptosis induced anticancer activity.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported