WEHI-150

• Description :

  WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslink[1].

• UNSPSC :

  12352005

• Target :

  DNA Alkylator/Crosslinker

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/wehi-150.html

• Solubility :

  10 mM in DMSO

• Smiles :

  NCCNCCNC1=CC=C(C2=C1C(C3=C(C=CC(O)=C3C2=O)O)=O)NCCNCCN

• Molecular Formula :

  C22H30N6O4

• Molecular Weight :

  442.51

• References & Citations :

  [1]Pumuye PP, et al. Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features. Bioorg Med Chem. 2020 Feb 1;28 (3) :115260.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [70492-21-6]