WEHI-P8

• Target:

  SARS-CoV

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  WEHI-P8 is an orally active inhibitor targeting the coronavirus papain-like protease (PLpro) . It inhibits SARS-CoV-2 PLpro with an IC50 of 12 nM and demonstrates excellent cellular activity with an EC50 of 298 nM. Additionally, WEHI-P8 has protective effects in mice against prolonged lung and brain symptoms caused by SARS-CoV-2. This compound is applicable for research on post-COVID-19 syndrome.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C