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HDAC6-IN-9

CAT: 0804-HY-147731-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147731-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC6-IN-9 (compound 12c) is a potent and selective HDAC6 inhibitor with IC50 values of 11.8, 15.2, 4.2, 139.6, 21.3 nM for HDAC1, HDAC3, HDAC6, HDAC8, HDAC10, respectively. HDAC6-IN-9 shows anti-proliferative activities[1].
CAS Number
2796282-58-9
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac6-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C2C=CC=CC2=C1)CC3=CC=C(C=C3)C(NO)=O
Molecular Formula
C19H16N2O3
Molecular Weight
320.34
References & Citations
[1]Li X, et al. Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy. Bioorg Chem. 2022 Aug;125:105874.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC10; HDAC3; HDAC6; HDAC8

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