PROTAC Hemagglutinin Degrader-1

PROTAC Hemagglutinin Degrader-1

• CAS Number: 3031330-66-9
• UNSPSC Description: PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity[1].
• Target Antigen: Influenza Virus; PROTACs
• Type: Reference compound
• Related Pathways: Anti-infection;PROTAC
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/protac-hemagglutinin-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)[C@H](C(C)(C)C)NC(CCOCCOCCOCCNC([C@]45[C@](CC(C)(CC5)C)([H])C6=CC[C@@]([C@@]7([C@@](C(C)([C@H](CC7)O)C)([H])CC8)C)([H])[C@]8(C)[C@@]6(CC4)C)=O)=O
• Molecular Weight: 1072.48
• References & Citations: [1]Li H, et al. Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders. J Med Chem. 2022 May 26;65(10):7154-7169.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported