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BTK-IN-12

CAT: 0804-HY-147582Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147582Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-12 is a potent BTK inhibitor with IC50s of 1.2 nM and 0.8 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022037649A1; compound 8) [1].
CAS Number
2762043-53-6
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-in-12.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1C(NCC2=CC=C(C=C2)C3=C4C(N)=NC=CN4C(C5CCC(OC5)CO)=N3)=O)F
Molecular Formula
C27H28FN5O4
Molecular Weight
505.54
References & Citations
[1]Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. WO2022037649A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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