ATR-IN-15

CAT: 0931-T61587-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61587-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2756665-52-6

Target

Others, ATM/ATR, DNA-PK, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, Others, DNA Damage/DNA Repair

Bioactivity

ATR-IN-15 (compound 1) is a highly potent, orally active ATR kinase inhibitor with an IC50 of 8 nM. It also exhibits inhibitory activity against human colon tumor cells LoVo, DNA-PK, and PI3K, with IC50 values of 47, 663, and 5131 nM, respectively [1].

Smiles

CC=1N2C(=C(N1)C=3C=CNN3)N=C(C=C2N4[C@H](C)COCC4)C=5N(C)N=CC5

Molecular Formula

C19H22N8O

Molecular Weight

378.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MBS5804289	ATR-IN-15
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