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NBTIs-IN-6

CAT: 0804-HY-146816Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146816Size:1 Each
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Description
NBTIs-IN-6 is a bacterial topoisomerase inhibitor with certain antibacterial activity. Among them, the MIC90 for fluoroquinolone-resistant MRSA was 2 μg/mL[1].
CAS Number
2422893-97-6
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nbtis-in-6.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12OC[C@@H]([C@]1(OC[C@@]2(CCC3=C(C=NC4=CC=C(N=C43)OC)F)O)[H])NCC5=NC=C6OCCOC6=C5
Molecular Formula
C25H27FN4O6
Molecular Weight
498.50
References & Citations
[1]Antony Okumu, et al. Novel bacterial topoisomerase inhibitors derived from isomannide. Eur J Med Chem. 2020 Aug 1;199:112324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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