AChE/BChE-IN-3

• Description:

  AChE/BChE-IN-3 (BMC-1) is a dual AChE and BChE inhibitor with IC50 values of 6.08 μM and 0.383 μM against electric eel AChE (elAChE) and equine serum BChE (eqBChE), respectively[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ache-bche-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC1=CC=CC(C(O)CNC(C)(C)C)=C1)N(C)C

• Molecular Formula:

  C15H24N2O3

• Molecular Weight:

  280.36

• References & Citations:

  [1]Wu J, et al. Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase. Bioorg Med Chem. 2020 Mar 1;28 (5) :115324.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AChE; BChE

• CAS Number:

  [2410992-65-1]