Axl-IN-6
CAT:
804-HY-146615
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Axl-IN-6
- CAS Number: 2642224-22-2
- UNSPSC Description: Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].
- Target Antigen: TAM Receptor
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/axl-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: CC(OC1=CC=C(C=C1)C2=CC=CC3=CN=C(N=C32)NC4=CC5=C(CC[C@@H](CC5)N6CCCC6)C=C4)C
- Molecular Weight: 492.65
- References & Citations: [1]Zhang LL, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.[published online ahead of print, 2022 Apr 6]. Eur J Med Chem. 2022;237:114316.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported