EGFR-IN-54

CAT: 0804-HY-146474Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-146474Size:1 Each

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Description

EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].

CAS Number

2418549-30-9

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-54.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(NC(NC2=CC=C(OCO3)C3=C2)=S)C=C1)(NC4=NC=CS4)=O

Molecular Formula

C17H14N4O4S3

Molecular Weight

434.51

References & Citations

[1]Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EGFR/ErbB1/HER1

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Catalog	Name
T62457-01	EGFR-IN-54
GTR18903701-01	Kisspeptin-54 (27-54)
H-5542.0001	Kisspeptin-54 (27-54) (human)
E-PP-1431-01	Kisspeptin-54 (27-54), human
GTR18890855	Human Kisspeptin-54 (27-54) peptide
PE-89212-01	Kisspeptin-54 (27-54) (Human) Peptide
T86643-01	HSD17B13-IN-54
T82088-01	ICMT-IN-54
MBS3616353-01	IM-54
JH918402	Oligopeptide-54

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