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ICMT-IN-54

CAT: 0931-T82088-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82088-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
908856-14-4
Target
Others, Transferase
Related Pathways
Metabolism, Others
Bioactivity
ICMT-IN-54 (compound 7c), an adamantyl analogue, serves as an ICMT inhibitor with an IC50 value of 12.4 μM, targeting the methylation process facilitated by ICMT. It specifically inhibits the methylation of BFC (N-biotinyl- (6-aminohexanoic) -S-farnesyl-L-cysteine) in Saccharomyces cerevisiae expressing ICMT, marking an indirect inhibition of ICMT-mediated methylation [1].
Smiles
C(N[C@@H](CSC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)C(O)=O)(=O)C12CC3CC(C1)CC(C2)C3
Molecular Formula
C29H45NO3S
Molecular Weight
487.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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