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AT1R antagonist 2

CAT: 0804-HY-146436Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146436Size:1 Each
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Description
AT1R antagonist 2 (compound 6) is a potent AT1R selective ligand. AT1R antagonist 2 exhibits a fair AT1R affinity, with a Ki of 26 nM[1].
CAS Number
2848719-76-4
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/at1r-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
CCCCOC(NS(=O)(C1=C(N=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C(CC)=NC4=C3N=C(C=C4C)C)=O)=O
Molecular Formula
C29H37N5O4S2
Molecular Weight
583.77
References & Citations
[1]Bolteau R, et al. Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine. Eur J Med Chem. 2020 Mar 1;189:112078.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT1 Receptor

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