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ANO1-IN-2

CAT: 0804-HY-146321Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146321Size:1 Each
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Description
ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1].
CAS Number
637314-12-6
UNSPSC
12352005
Target
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ano1-in-2.html
Solubility
10 mM in DMSO
Smiles
NC(C1=C(SC2=C1CCC2)NC(NC(C3=CC=C(C=C3)Cl)=O)=S)=O
Molecular Formula
C16H14ClN3O2S2
Molecular Weight
379.88
References & Citations
[1]Choi SH, et al. Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers. Eur J Med Chem. 2020 Dec 15;208:112688.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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