ANO1 antibody

• Background :

  ANO1 also named as DOG1, ORAOV2, TAOS2 and TMEM16A, acts as a calcium-activated chloride channel. It is required for normal tracheal development. ANO1 (or DOG1) is used as an aid in the identification and diagnosis of gastrointestinal stromal tumors (GIST) within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist. The immunogen is the C-terminal of ANO1. This antibody can recognize isoform1 and isoform2 of human ANO1.

• Synonyms :

  Anoctamin-1|Discovered on gastrointestinal stromal tumors protein 1|Oral cancer overexpressed protein 2|Transmembrane protein 16A|Tumor-amplified and overexpressed sequence 2|ANO1|DOG1|ORAOV2|TAOS2|TMEM16A

• Gene ID :

  55107

• UniProt :

  Q5XXA6

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Transmembrane protein 16A

• Target :

  ANO1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC

• Field of Research :

  Cancer, Immunology, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC