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ANO1-IN-4

CAT: 0931-T203487-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203487-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2098490-06-1
Target
Chloride channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 μM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.
Smiles
O=C(NC=1C=CC=CC1C)C2=C(SC3=C2CCCCC3)NC(=O)C(F)(F)Br
Molecular Formula
C19H19BrF2N2O2S
Molecular Weight
457.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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