INOS-IN-2

• Description :

  INOS-IN-2 (Compound 53) is a potent down-regulator of inducible nitric oxide synthase (iNOS) protein. iNOS-IN-2 effectively inhibits the NO production (IC50=6.4 μM) . iNOS-IN-2 has a potential therapeutic effect on chronic inflammation[1].

• UNSPSC :

  12352005

• Target :

  NO Synthase

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/inos-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(OCCCN3CCOCC3)C(OC)=C2

• Molecular Formula :

  C25H31NO7

• Molecular Weight :

  457.52

• References & Citations :

  [1]Youzhe Yang, et al. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation. Eur J Med Chem. 2020 May 1;193:112216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  INOS

• CAS Number :

  [2419891-42-0]